Thanks to the ease of the administration, the oral cavity is an attractive site for the delivery of drugs. Oral mucosal drug delivery enables mucosal (local effect) and transmucosal (systemic effect) drug administration.
The main obstacles that drugs meet when administered via the buccal route are due to the limited absorption area and the barrier properties of the mucosa. Dow offers solutions to help overcome those obstacles.
Solutions for Mucosal Bioadhesives:
POLYOX™ polymers offer a number of important properties for mucoadhesion, including water solubility, hydrophilicity, high molecular weight, hydrogen bonding functionality, and good biocompatibility. The flexibility to penetrate the mucus membrane and hydrogen bonding groups make POLYOX™ resins effective for buccal and oral care.