About two-thirds of all medications are dispensed as oral solid dosage forms (OSDFs), and half of these OSDFs are tablets. DuPont pioneered several excipients used in the formulation of tablets, and today 1 of every 3 tablets produced contain our ingredients.
While they look simple and elegant, tablets are complex API pharma formulations that need excipients to serve various functionalities:
Our broad and unique portfolio provides all those attributes. As the first supplier to ever develop leading tablet excipients, we’ve honed a deep experience over decades to ensure your tablet formulations in the OSD process are successful. The choice of excipients depends on the API, the tablet type, the desired release profile, and the manufacturing process.
Excipient |
Product Recommendation |
---|---|
Binder and compression aid |
|
Wet binder |
|
Disintegrant |
|
Lubricant |
|
Immediate release aesthetic coating |
Tablet Types |
Specific Functionality |
Product Recommendation |
---|---|---|
Immediate release |
Chewable tablets Orally disintegrated tablets |
Avicel® HFE, Avicel® CE-15 Ac-Di-Sol® SD-711, Ac-Di-Sol® SDW 802 Alubra™ |
|
Taste Masking |
ETHOCEL™ STD 4, 7, 10 or 20 PRM, ETHOCEL™ HP Aquacoat® ECD (Aqueous Coating) |
Modified release tablets |
Controlled Release Hydrophilic Matrices |
METHOCEL™ K100LV, K4M, K15M, K100M, K200M, E4M, E10M (PRM or PRM CR) METHOCEL™ K100 LV PRM DC2, K4M PRM DC2, K100M DC2 POLYOX™ WSR-205, 1105, N12K, N60K, 301, 303, Coagulant Protanal® CR8133, CR8223, and Manucol® LKX Gelcarin® GP-379, GP-812, and Viscarin® GP-209 |
|
Controlled Release Hydrophobic Matrices |
ETHOCEL™ STD 7 FP, ETHOCEL™ STD 10 FP, ETHOCEL™ STD 100 FP |
|
Controlled Release Coating |
ETHOCEL™ STD 4, 7, 10, 20 PRM (Solvent Film Coating) ETHOCEL™ HP (Dry Powder Coating) Aquacoat® ECD 30 (Aqueous Coating) Aquacoat® CPD 30 (Delayed Release Aqueous Coating) |
|
Osmotic pump |
POLYOX™ N10, N80, WSR Coagulant, WSR-301, WSR-303 |
We want to help you be successful in whatever application you are considering, so please contact us if you need more assistance. Our experts are eager to tackle your challenges.
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