Abuse Deterrence

Over the past decade, the abuse of prescription opioid drugs became a national health crisis in the United States.

Pharmaceutical companies, the Food and Drug Administration, and other government agencies are confronting opioid abuse by developing and commercializing various abuse-deterrent drug delivery technologies.

Enabling Technologies

DowDuPont offers a range of chemistries for abuse deterrence applications.

  • POLYOX™, a high-molecular-weight polyethylene oxide, is a leading technology in this space, providing tamper resistant properties.

  • AMBERLITE™ and DUOLITE™ ion exchange resins prevent immediate release.

 
 
 

Related Applications

Thumb_Excipients_APIStability.jpg
Dow offers solutions to protect APIs from environmental conditions and increase the stability of a drug’s long-term quality, efficacy and safety
yellow_capsules_shutterstock_56239201_3_Card_Layout.png
Utilizing a novel patented process (alginate) this technology provides a unique seamless, enteric, vegetarian alternative to gelatin soft capsules in one unit process for pharmaceutical and nutraceutical applications.
mother_and_daughter_shutterstock_15995386_3Card_Layout.png
Alginate-based impressions are attractive as orthodontic study models for a variety of reasons. These are fast setting at room temperature, easy to prepare, and very cost effective.
shutterstock_562215688_3_cart_Layout.png
An enteric coating resists disintegration in the low pH of the stomach and is dissolved in the neutral pH environment of the intestine
iStock-179133772.png
Suspensions are pharmaceutically stable dispersions of an insoluble or sparingly-soluble drug in a liquid vehicle, usually an aqueous solution. They can be ready-to-use or reconstitutable, where the drug is mixed with other ingredients in the dry state and reconstituted with water at the time of dispensing to the patient.
shutterstock_564214432_3_cart_Layout.png
Use of Avicel® DG dramatically increases tablet hardness, improves yields and provides good flow and a robust ribbon during the initial compaction phase
shutterstock_373422979_3_cart_Layout.png
Dow’s excipients for controlled or modified release tablet and capsule formulations.
4.2.10_Thumb_nasal_delivery.jpg
Dow’s excipients for the nasal administration of pharmaceuticals.
iStock-582280216.png
Chewable tablets as a dosage form are growing in popularity. Palatable chewable tablets offer convenience for customers, broaden the applicability of formulations to pediatric or geriatric markets, and increase patient compliance
Thumb_Excipients_RheologyModifier.jpg
Rheology modifier, dosage form, liquid dosage forms, semi-solid formulations, thickeners, topical applications, thickening agent, Dow, Dow Pharma Solutions, METHOCEL, WALOCEL
Thumb_Excipients_SolubilityEnhancement.jpg
Dow’s portfolio of solubility enhancing excipients for drug compounds with low aqueous solubility.
4.2.3_Thumb_tabelt_coating.jpg
Dow’s excipients for film tablet coatings are tough, printable, economical and highly consistent.
Thumb_Applications_TasteMasking.jpg
Dow’s excipients for taste masking applications in the oral drug delivery of tablets.
iStock-467924581.png
Topical formulations enable local delivery of a drug to a specific site of action without systemic exposure and may be creams, gels, or sprays.

Get Started

DuPont cares about your privacy. Your personal information (name, email, phone number and other contact data) will be stored in chosen customer systems primarily hosted in the United States. This information will be used by DuPont, its affiliates, partners, and selected third parties in other countries to provide you with the product or service information requested. To learn more, please visit www.privacy.dupont.com. By providing your personal information, you agree to the terms and conditions of this Privacy Statement.

 
 
 
/content/dupont/amer/us/en/nutrition-biosciences/references/contact-us.html /content/dupont/amer/us/en/nutrition-biosciences/references/corporate-contact-us.html /content/dupont/amer/us/en/nutrition-biosciences/references/subscribe.html