Modified Release

Controlled release (CR) oral drug delivery systems are employed to improve patient compliance and therapeutic outcomes. Modified release (MR) dosage forms can be utilized to reduce the number of times the patient has to administer medication over the course of the day. They can also be utilized to prolong the time in which the systemic blood concentration remains within the therapeutic window, while avoiding potential adverse events from spikes in drug concentration.

Enabling Technologies

We offer a portfolio of functional polymeric excipients, which are utilized to formulate various modified release dosage forms like hydrophilic matrix tablets, inert matrices, barrier-coated multiparticulates and osmotic pump technology. Our strength is our commitment to quality and consistency. Our products are fully certified for pharmaceutical use, come in a wide variety of molecular weights and offer innovations for all kinds of tablet designs

 
 
 

Related Applications

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Dow’s excipients for drug abuse deterrence applications provide tamper resistant properties.
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Dow offers solutions to protect APIs from environmental conditions and increase the stability of a drug’s long-term quality, efficacy and safety
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Utilizing a novel patented process (alginate) this technology provides a unique seamless, enteric, vegetarian alternative to gelatin soft capsules in one unit process for pharmaceutical and nutraceutical applications.
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Alginate-based impressions are attractive as orthodontic study models for a variety of reasons. These are fast setting at room temperature, easy to prepare, and very cost effective.
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An enteric coating resists disintegration in the low pH of the stomach and is dissolved in the neutral pH environment of the intestine
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Suspensions are pharmaceutically stable dispersions of an insoluble or sparingly-soluble drug in a liquid vehicle, usually an aqueous solution. They can be ready-to-use or reconstitutable, where the drug is mixed with other ingredients in the dry state and reconstituted with water at the time of dispensing to the patient.
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Use of Avicel® DG dramatically increases tablet hardness, improves yields and provides good flow and a robust ribbon during the initial compaction phase
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Dow’s excipients for the nasal administration of pharmaceuticals.
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Chewable tablets as a dosage form are growing in popularity. Palatable chewable tablets offer convenience for customers, broaden the applicability of formulations to pediatric or geriatric markets, and increase patient compliance
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Rheology modifier, dosage form, liquid dosage forms, semi-solid formulations, thickeners, topical applications, thickening agent, Dow, Dow Pharma Solutions, METHOCEL, WALOCEL
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Dow’s portfolio of solubility enhancing excipients for drug compounds with low aqueous solubility.
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Dow’s excipients for film tablet coatings are tough, printable, economical and highly consistent.
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Dow’s excipients for taste masking applications in the oral drug delivery of tablets.
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Topical formulations enable local delivery of a drug to a specific site of action without systemic exposure and may be creams, gels, or sprays.

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