Tablet Coating

Tablet coating serves a number of purposes that are useful for improving the desired properties of the end-use product, such as protection, ease of swallowing, modified release and taste-masking.

Enabling Technologies

METHOCEL™ cellulose ethers form strong films with good adhesion, leading to clear, sharp coatings that are nonionic and compatible with dyes and pigments. They are excellent surfaces for printing and to ease swallowing.

Low-viscosity WALOCEL™ C grades, available as powder and granular grades, offer highly transparent solutions, which makes these grades ideal for tablet coatings.

Water-insoluble ETHOCEL™ ethyl cellulose polymers form strong films with good adhesion. ETHOCEL™ films offer versatility in drug release rates and can be applied to a wide variety of substrates in most commonly used pharmaceutical processes.

ENTERACT™ HPMCAS polymers offer flexible coatings for enteric delivery that resist disintegration in the stomach and enteric coatings feature low reactivity, low tack and can be efficiently applied.

 
 
 

Related Applications

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Dow’s excipients for drug abuse deterrence applications provide tamper resistant properties.

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Dow offers solutions to protect APIs from environmental conditions and increase the stability of a drug’s long-term quality, efficacy and safety

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Utilizing a novel patented process (alginate) this technology provides a unique seamless, enteric, vegetarian alternative to gelatin soft capsules in one unit process for pharmaceutical and nutraceutical applications.

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Alginate-based impressions are attractive as orthodontic study models for a variety of reasons. These are fast setting at room temperature, easy to prepare, and very cost effective.

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Dow’s excipients for the enteric coating of pharmaceutical tablets.

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An enteric coating resists disintegration in the low pH of the stomach and is dissolved in the neutral pH environment of the intestine

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Suspensions are pharmaceutically stable dispersions of an insoluble or sparingly-soluble drug in a liquid vehicle, usually an aqueous solution. They can be ready-to-use or reconstitutable, where the drug is mixed with other ingredients in the dry state and reconstituted with water at the time of dispensing to the patient.

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Use of Avicel® DG dramatically increases tablet hardness, improves yields and provides good flow and a robust ribbon during the initial compaction phase

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Dow’s excipients for controlled or modified release tablet and capsule formulations.

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Dow’s excipients for the nasal administration of pharmaceuticals.

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Chewable tablets as a dosage form are growing in popularity. Palatable chewable tablets offer convenience for customers, broaden the applicability of formulations to pediatric or geriatric markets, and increase patient compliance

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Rheology modifier, dosage form, liquid dosage forms, semi-solid formulations, thickeners, topical applications, thickening agent, Dow, Dow Pharma Solutions, METHOCEL, WALOCEL

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Dow’s portfolio of solubility enhancing excipients for drug compounds with low aqueous solubility.

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Dow’s excipients for taste masking applications in the oral drug delivery of tablets.

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Topical formulations enable local delivery of a drug to a specific site of action without systemic exposure and may be creams, gels, or sprays.

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