The taste of orally delivered drugs is extremely important to encourage patient acceptability and compliance. Acceptable taste can help to determine market penetration and the commercial success of a new active pharmaceutical ingredient or a new dosage form. Unfortunately, the majority of orally administered, moderately water-soluble drugs are inherently very bitter. This is especially problematic with pediatric suspensions, since children are more sensitive to taste than adults. Hence, the ability to taste-mask is an important consideration for drug formulators.

Enabling Technologies

With DuPont AMBERLITE™ and DUOLITE™ resins, the drug is not released in the mouth, minimizing negative taste experience. When in contact with gastrointestinal fluids, the drug is released and then absorbed in the usual way. The resin passes through the GI tract without being absorbed.

ETHOCEL™ ethylcellulose polymers can be formulated into either clear or opaque films of varying thicknesses, for

different dissolution rates and taste-masking functionality.


Related Applications


Dow’s excipients for drug abuse deterrence applications provide tamper resistant properties.


Dow offers solutions to protect APIs from environmental conditions and increase the stability of a drug’s long-term quality, efficacy and safety


Utilizing a novel patented process (alginate) this technology provides a unique seamless, enteric, vegetarian alternative to gelatin soft capsules in one unit process for pharmaceutical and nutraceutical applications.


Alginate-based impressions are attractive as orthodontic study models for a variety of reasons. These are fast setting at room temperature, easy to prepare, and very cost effective.


Dow’s excipients for the enteric coating of pharmaceutical tablets.


An enteric coating resists disintegration in the low pH of the stomach and is dissolved in the neutral pH environment of the intestine


Suspensions are pharmaceutically stable dispersions of an insoluble or sparingly-soluble drug in a liquid vehicle, usually an aqueous solution. They can be ready-to-use or reconstitutable, where the drug is mixed with other ingredients in the dry state and reconstituted with water at the time of dispensing to the patient.


Use of Avicel® DG dramatically increases tablet hardness, improves yields and provides good flow and a robust ribbon during the initial compaction phase


Dow’s excipients for controlled or modified release tablet and capsule formulations.


Dow’s excipients for the nasal administration of pharmaceuticals.


Chewable tablets as a dosage form are growing in popularity. Palatable chewable tablets offer convenience for customers, broaden the applicability of formulations to pediatric or geriatric markets, and increase patient compliance


Rheology modifier, dosage form, liquid dosage forms, semi-solid formulations, thickeners, topical applications, thickening agent, Dow, Dow Pharma Solutions, METHOCEL, WALOCEL


Dow’s portfolio of solubility enhancing excipients for drug compounds with low aqueous solubility.


Dow’s excipients for film tablet coatings are tough, printable, economical and highly consistent.


Topical formulations enable local delivery of a drug to a specific site of action without systemic exposure and may be creams, gels, or sprays.

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